Microbicides

  • Manual for Conducting a Gender Analysis for Microbicide Introduction

    This manual provides guidance for conducting a gender analysis in a country preparing to introduce microbicides. A gender analysis can strengthen the effectiveness of health and development programming by identifying gender inequalities that may affect program outcomes and potential ways to address those inequalities.The manual outlines the steps to conducting a gender analysis for microbicide introduction, shares lessons learned from pilot testing in Kenya and South Africa, and provides tools and resources for conducting a gender analysis for microbicide introduction.

  • Engaging Male Partners in Women's Microbicide Use: Evidence and Recommendations

    Vaginal microbicides are considered a groundbreaking HIV prevention tool because women can initiate their use, but male partners have played an important role in product acceptability and adherence to study regimens in clinical trials. This document synthesizes the evidence on men’s roles in women’s use of microbicides in clinical trials and makes recommendations for engaging male partners in future microbicide research and product introduction.

  • Communicating about Microbicides with Women in Mind: Prototype Materials

    The Communicating about Microbicides with Women in Mind project worked with Artful Eyes Productions, a local Kenyan creative agency, to develop a suite of evidence-based, prototype communication materials to support the introduction of vaginal microbicide gel in Kenya should a microbicide be proven effective. Specifically designed to promote vaginal gel use in Kenya, these materials will need to be adapted for use in other countries or for other HIV prevention products.

  • Communicating About Microbicides with Women in Mind (fact sheet)

    The Communicating about Microbicides with Women in Mind project developed a two-page document highlighting the project’s major accomplishments, including details about the three project phases conducted in Kenya: 1) landscape analysis, 2) materials development and pretesting, and 3) materials assessment and key results.

  • Communicating about Microbicides with Women in Mind: Communication Strategy and Adaptation Guide

    This final report for the Communicating about Microbicides with Women in Mind project was written to: 1) document the promise of vaginal microbicide gel as a new HIV prevention product for women, 2) describe the project’s experience with materials development, 3) provide a sample microbicide communication strategy for Kenya, and 4) outline a process for updating and adapting the materials for use in other countries or with other new HIV prevention methods.

  • Understanding HIV Drug Resistance in the Context of Microbicides and Pre-Exposure Prophylaxis (PrEP)

    This clear and accessible two-page fact sheet explains the basic concept of HIV drug resistance and how it occurs by posing and answering four key questions. The document includes simple, illustrative diagrams and a summary of important points to remember.

  • The Rectal Revolution is Here - Video and Facilitator's Guide

    “The Rectal Revolution is Here: An Introduction to Rectal Microbicide Clinical Trials,” is designed to educate communities affected by HIV about the development of rectal microbicides and the importance of participating in clinical trials to speed the search for new HIV prevention methods. Produced by Paw Print Productions of Cape Town, South Africa, the video is available for viewing on YouTube in English, Spanish, and Thai. A facilitator's guide is also available in English, Spanish, and Thai.

  • Sexual Communication among Married Couples in the Context of a Microbicide Clinical Trial and Acceptability Study in Pune, India

    The results of a study exploring couple-level sexual communication and socio-cultural norms that influence couples’ communication about sex are reported in this 14-page paper, which was published in the journal 

  • Sister Studies: The Ring Study and ASPIRE

    The Ring Study and ASPIRE (A Study to Prevent Infection with a Ring for Extended Use) are described in this fact sheet. The two related trials showed that monthly use of a vaginal ring that delivers the antiretroviral drug dapivirine can help prevent HIV infection in women and is safe for long-term use.

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