The results of a Phase II trial of reduced-glycerin 1% tenofovir gel among men who have sex with men and transgender women, published in Clinical Infectious Diseases, found that rectal application of the gel was safe and acceptable. Adherence and reported likelihood of future use were similar for intermittent use of the gel and a daily oral PrEP regimen, but lower for the daily gel regimen.
The World Health Organization (WHO) provides guidance on the diagnosis of HIV infection, the use of antiretroviral drugs for treating and preventing HIV infection, and the care of people living with HIV in this update of its 2013 consolidated guidelines.
Published in advance of the second edition of the World Health Organization's consolidated guidelines on the use of antiretrovirals (WHO, 2016) this policy brief summarizes the 10 recommendations in the updated guidelines and highlights what is new, based on an extensive review of the evidence conducted in 2015.
This page provides links to articles or article abstracts from the FEM-PrEP trial of the effectiveness of pre-exposure prophylaxis for HIV prevention among women at high risk of acquiring HIV infection. It includes a section on articles about adherence to daily PrEP among the trial participants.
Produced collaboratively by UNAIDS, WHO, and AVAC, this publication is intended to complement WHO’s recommendations on pre-exposure prophylaxis (PrEP) and support the optimal use of oral PrEP to protect individuals and contribute to ending the AIDS epidemic.
An 11-page document from UNAIDS, WHO, and AVAC answers questions about oral pre-exposure prophylaxis (PrEP), addressing issues including safety, eligibility, potential risk compensation, implementation, and cost-effectiveness.
The findings from an assessment of the feasibility and potential impact of delivering antiretroviral (ARV)-based oral and injectable pre-exposure prophylaxis (PrEP) and vaginal microbicide gels in South Africa are summarized in this brief.
The findings from an assessment of the feasibility and potential impact of delivering antiretroviral (ARV)-based oral and injectable pre-exposure prophylaxis (PrEP) and vaginal microbicide gels in Kenya are summarized in this brief.
This guidance offers practical advice on how to engage men who have sex with men in research trials of promising HIV prevention and treatment interventions, including HIV vaccines, rectal microbicides, combinations of prevention methods, and pre-exposure prophylaxis. The guidance aims to maximize the benefits and minimize the risks to men who have sex with men, communities, and researchers.