rectal microbicides

  • Preparing for Rectal Microbicides: Sociocultural Factors Affecting Product Uptake Among Potential South American Users

    Published in the June 2014 issue of the American Journal of Public Health, this article reports on the results of a qualitative study conducted among 140 men who have sex with men and transgender women in Lima and Iquitos, Peru, and Guayaquil, Ecuador, to explore their views on rectal microbicides and identify factors that could affect uptake of a rectal microbicide.



  • The Rectal Revolution is Here - Video and Facilitator's Guide

    “The Rectal Revolution is Here: An Introduction to Rectal Microbicide Clinical Trials,” is designed to educate communities affected by HIV about the development of rectal microbicides and the importance of participating in clinical trials to speed the search for new HIV prevention methods. Produced by Paw Print Productions of Cape Town, South Africa, the video is available for viewing on YouTube in English, Spanish, and Thai. A facilitator's guide is also available in English, Spanish, and Thai.

  • Rectal Microbicides

    The reasons why rectal microbides are needed, challenges to their development, and the results of clinical trials on their safety and acceptability are described in this fact sheet.

  • On the Map: Ensuring Africa’s Place in Rectal Microbicide Research and Advocacy

    This is a 29-page report on a strategy development meeting, hosted by International Rectal Microbicide Advocates in December 2011 in Addis Ababa, Ethiopia. The meeting brought together African stakeholders and allies representing a wide array of perspectives, experiences, and regions to develop action steps for an African rectal microbicide research and advocacy agenda. The group prioritized seven key action areas.

  • MTN-017

    Links are provided to information about MTN-017. The first Phase II trial of a rectal microbicide, MTN-017 found that a reduced-glycerin formulation of tenofovir gel was safe when used daily and before and after sex. Study participants were just as likely to follow through using an anti-HIV gel with anal sex as they were to using daily oral pre-exposure prophylaxis (PrEP).