Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women

The results of The Ring Study, a randomized controlled trial that evaluated the safety and efficacy of extended use of a vaginal ring containing dapivirine for the prevention of HIV infection among women in South Africa and Uganda,were published December 1, 2016, in The New England Journal of Medicine. The authors concluded that the dapivirine ring was not associated with any safety concerns and was associated with a rate of acquisition of HIV-1 infection that was lower than the rate with placebo.

Length: 
10 pages
Year: 
2016
Organization: 
International Partnership for Microbicides
Languages: 
English
Author(s): 
Nel A, van Niekerk N, Com M, Kapiga S, et al. for The Ring Study Team