Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women
Published in the New England Journal of Medicine on December 1, 2016, this article reports on the results of A Study to Prevent Infection with a Ring for Extended Use (ASPIRE). The authors conclude that a monthly vaginal ring containing dapivirine reduced the risk of HIV-1 infection among African women, with increased efficacy among subgroups of the study population with evidence of more consistent use of the ring.